Coordinated work reveals plant evolution

Phylogenetic expression profiling reveals widespread coordinated evolution of gene expression

Modeling Coordinated Work Environments

This paper describes a coordination model for collaborative work. The model utilizes an assemblage of several organization units with specific goals and structure, populated by actors, work practices and artefacts. Coordination work is defined by interdependencies existing in work practices which can be prerequisite, simultaneous or by means of sharing of resources. Coordination between communi...

Genome-wide network model capturing seed germination reveals coordinated regulation of plant cellular phase transitions.

Seed germination is a complex trait of key ecological and agronomic significance. Few genetic factors regulating germination have been identified, and the means by which their concerted action controls this developmental process remains largely unknown. Using publicly available gene expression data from Arabidopsis thaliana, we generated a condition-dependent network model of global transcripti...

Coordinated evolution of the hepatitis C virus.

Hepatitis C virus is a genetically heterogeneous RNA virus that is a major cause of liver disease worldwide. Here, we show that, despite its extensive heterogeneity, the evolution of hepatitis C virus is primarily shaped by negative selection and that numerous coordinated substitutions in the polyprotein can be organized into a scale-free network whose degree of connections between sites follow...

Coordinated Distributed Diagram Transformation for Software Evolution

We present an approach to maintaining consistency between code and specification during refactoring, where a specification comprises several UML diagrams of different types. Code is represented as a flowgraph, and the flowgraph and UML diagrams constitute different views of a software system. A refactoring is modelled as a set of distributed graph transformations, organized into transformation ...